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1.
Prenat Diagn ; 40(13): 1755-1758, 2020 12.
Article in English | MEDLINE | ID: covidwho-1070796

ABSTRACT

Even though the global COVID-19 pandemic may affect how medical care is delivered in general, most countries try to maintain steady access for women to routine pregnancy care, including fetal anomaly screening. This means that, also during this pandemic, fetal anomalies will be detected, and that discussions regarding invasive genetic testing and possibly fetal therapy will need to take place. For patients, concerns about Severe Acute Respiratory Syndrome-Corona Virus 2 will add to the anxiety caused by the diagnosis of a serious fetal anomaly. Yet, also for fetal medicine teams the situation gets more complex as they must weigh up the risks and benefits to the fetus as well as the mother, while managing a changing evidence base and logistic challenges in their healthcare system.


Subject(s)
COVID-19 , Fetal Therapies , Pandemics , Disasters , Female , Humans , Infectious Disease Transmission, Vertical , Pregnancy , Pregnancy Complications, Infectious
3.
J Perinat Med ; 48(5): 438-440, 2020 Jun 25.
Article in English | MEDLINE | ID: covidwho-253834

ABSTRACT

The novel coronavirus disease 2019 (COVID-19) pandemic is causing concern also for the management and outcome of COVID-19-positive pregnant women and their offspring, as reported cases are rare. Current evidence suggests the association of COVID-19 infection in pregnancy with both severe maternal morbidity requiring intensive care and perinatal complications (preterm birth with consequent neonatal morbidity and even perinatal death). Most of the reported cases focused specifically on the maternal outcomes and possible vertical transmission, but less attention has been paid to fetus as a patient in such pregnancies. The use of antenatal steroids and fetal neuroprotection with magnesium sulfate is clearly underreported. Several recently issued guidelines suggest lowering the upper gestational age for antenatal steroid administration and also advocate extreme caution or even restraining from the use of magnesium sulfate. Also, the rate of cesarean deliveries among COVID-19 women is unacceptably high. Here we provide arguments for NOT changing the existing guidelines and caution against cesarean delivery that was the prevalent delivery mode in the reported cases and case series.


Subject(s)
Betacoronavirus , Coronavirus Infections/therapy , Fetal Therapies/methods , Pneumonia, Viral/therapy , Pregnancy Complications, Infectious/therapy , Prenatal Care/methods , Adrenal Cortex Hormones/therapeutic use , Anti-Inflammatory Agents/therapeutic use , COVID-19 , Coronavirus Infections/transmission , Delivery, Obstetric/methods , Female , Fetal Therapies/standards , Humans , Infectious Disease Transmission, Vertical/prevention & control , Magnesium Sulfate/therapeutic use , Neuroprotective Agents/therapeutic use , Pandemics , Pneumonia, Viral/transmission , Practice Guidelines as Topic , Pregnancy , Premature Birth/therapy , Premature Birth/virology , Prenatal Care/standards , SARS-CoV-2
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